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Synthesis of 1-hydroxyalkyl-3-substituted ureas and thioureas as a substrates for alcohol dehydrogenase]
Authors:O N Leonov  V M Shcherbakov  V M Devichenski?  L Iu Kriukova  E A Vorontsov  S L Kuznetsov  L N Kriukov
Institution:Institute of Biological Medicine, ul. Akademika Oparina 4, Mascow, 117815 Russia.
Abstract:A series of 1-(2-hydroxyethyl)- and 1-(3-hydroxyethyl)-3-substituted ureas and thioureas were synthesized. 1-(3-Hydroxyethyl)-3-acylthioureas were shown to be specific substrates for alcohol dehydrogenase in vitro.
Keywords:
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