Epigenetic Control of Lactate Dehydrogenase Subunit Assembly |
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Authors: | MIRIAM ROSENBERG |
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Affiliation: | 1.Department of Biology,Yale University,New Haven;2.Department of Medical Genetics,University of Pennsylvania School of Medicine,Philadelphia |
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Abstract: | Fish lactate dehydrogenase differs from the mammalian enzyme by virtue of tissue-specific non-random tetramerization of its two subunits, which can be random in vitro. The primary structures of the subunits are therefore not the sole determinants of the quaternary structure of the completed molecule. |
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