Anomalous Effects of Heterologous Normal Serum on Interferon Production in Mice |
| |
Authors: | ROBERT M FRIEDMAN ROLF F BARTH ROBERT STERN |
| |
Institution: | 1.Laboratory of Pathology,National Cancer Institute,;2.Laboratory of Biochemistry,National Institute of Dental Research, National Institutes of Health,Bethesda |
| |
Abstract: | WHILE studying the inhibitory effect of burro anti-mouse lymphocyte serum on the production of interferon in mice1, we investigated whether rabbit anti-mouse lymphocyte serum (ALS) had similar activity. There was some inhibition of interferon production after intraperitoneal injection of polyinosinic/polycytidylic acid (poly IC) in NIH Swiss strain mice pretreated with three doses of potent rabbit anti-mouse lymphocyte serum. Animals treated with normal rabbit serum, however, showed a similar inhibition of interferon production (Table 1), although normal burro serum had no effect1. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|