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Cytokinin and anticytokinin activity of some 4-substituted 1H-pyrazoles and 8-aza analogues of adenine
Authors:E. Karanov  V. Alexieva  E. Golovinsky  M. Haimova
Affiliation:(1) M. Popov Institute of Plant Physiology, Bulgarian Academy of Sciences, Bulgaria;(2) Institute of Molecular Biology, Bulgarian Academy of Sciences, Bulgaria;(3) Department of Organic Chemistry, University of Sofia, Bulgaria;(4) Acad. M. Popov Institute of Plant Physiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., BI 21, 1113 Sofia, Bulgaria
Abstract:Using specific bioassays i.e. radish cotyledon expansion, betacyanin synthesis in Amaranthus caudatus, and senescence retardation of isolated leaf explants, six 4-substituted 1-H pyrazoles and five 8-aza adenine analogues were tested for their cytokinin- and anticytokinin activity. Most of the pyrazole derivatives showed some cytokinin-like activity and enhanced the effect of 10–5 M BA. 8-Aza substituted adenines were found to be cytokinin antagonists; in the bioassays used they were inactive when applied alone but blocked the action of 10–5 M BA when applied simultaneously.
Keywords:cytokinins  anticytokinins  cytokinin antagonists  pyrazoles  8-aza adenines
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