Proinflammatory effect in whole blood by free soluble bacterial components released from planktonic and biofilm cells |
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| Authors: | Jan Oscarsson Maribasappa Karched Bernard Thay Casey Chen Sirkka Asikainen |
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| Institution: | 1.Oral Microbiology, Department of Odontology,Ume? University,Ume?,Sweden;2.Primary Oral Health Care, USC School of Dentistry,University of Southern California,Los Angeles,USA;3.Department of Medical Biochemistry and Microbiology,Uppsala Biomedical Center, Uppsala University,Sweden |
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| Abstract: | Background
Aggregatibacter actinomycetemcomitans is an oral bacterium associated with aggressive forms of periodontitis. Increasing evidence points to a link between periodontitis
and cardiovascular diseases, however, the underlying mechanisms are poorly understood. This study investigated the pathogenic
potential of free-soluble surface material, released from live planktonic and biofilm A. actinomycetemcomitans cells. |
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