Evolutionary Pareto-optimization of stably folding peptides |
| |
| Authors: | Wolfram Gronwald Tim Hohm Daniel Hoffmann |
| |
| Affiliation: | 1.Institute for Functional Genomics,University of Regensburg,Regensburg,Germany;2.Computer Engineering and Networks Laboratory,ETH Zurich,Zürich,Switzerland;3.Centre for Medical Biotechnology,University of Duisburg-Essen,Essen,Germany |
| |
| Abstract: | Background As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides have been discovered. This raises the question whether there may be more such peptides that are unknown as yet. These molecules could be helpful in basic research and medicine. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
