Susceptibility of peritoneal macrophages to rat cytomegalovirus infection |
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| Authors: | Cathrien A Bruggeman Gert Grauls Cees PA van Boven |
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| Institution: | Department of Medical Microbiology, University of Limburg, P.O. Box 616, 6200 MD Maastricht, The Netherlands |
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| Abstract: | Abstract Peritoneal macrophages from Lewis (Lew) and Brown Norway (BN) rats did not support rat cytomegalovirus (RCMV) replication. Intraperitoneal (i.p.) inoculation of virus into the rats resulted in a rapid clearance of virus from the peritoneal lavage fluid and an uptake of virus in the macrophages. The virus did not persist in the peritoneal macrophages of the rats. |
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| Keywords: | Rat cytomegalovirus peritoneal macrophages intrinsic antiviral activity |
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