The DVR gene family in embryonic development. |
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Authors: | K M Lyons C M Jones B L Hogan |
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Affiliation: | Department of Cell Biology, Vanderbilt University Medical School, Nashville, TN 37232. |
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Abstract: | The DVR gene family consists of at least 15 members, including decapentaplegic from Drosophila, Xenopus Vg1 and the mammalian bone morphogenetic protein genes, encoding secreted proteins closely related to transforming growth factor beta Genetic and biochemical evidence supports the idea that DVR proteins form part of a cascade of extracellular signalling molecules mediating inductive tissue interactions during development. |
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