Mechanism of effector cell blockade. III. The increased sensitivity of neonatal PFC to effector cell blockade |
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| Authors: | A W Boyd J W Schrader |
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| Institution: | Department of Pediatrics, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 U.S.A. |
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| Abstract: | The response to staphylococcal protein A (SPA) of unfractionated, T-cell-enriched (TCE), and T-cell-depleted (TCD) populations of both adult mononuclear cells (AMC) and cord blood mononuclear cells (CBMC) was studied. Adult unfractionated and TCE populations formed more T-lymphocyte colonies than did similar populations of CBMC. However, TCD populations of CBMC formed B-lymphocyte colonies at least as well as did the TCD population of AMC. These results suggest that B cells from CBMC may be more mature than CBMC T-cell populations. |
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| Keywords: | To whom all correspondence should be addressed: UTCHS 956 Court Avenue—Rm 3809 Memphis Tenn 38163 |
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