Germ cells are forever |
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| Authors: | Cinalli Ryan M Rangan Prashanth Lehmann Ruth |
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| Affiliation: | HHMI and Kimmel Center for Biology and Medicine of the Skirball Institute, Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA. |
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| Abstract: | Germ cells are the only cell type capable of generating an entirely new organism. In order to execute germline-specific functions and to retain the capacity for totipotency, germ cells repress somatic differentiation, interact with a specialized microenvironment, and use germline-specific networks of RNA regulation. |
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