| SMC蛋白的结构和功能 |
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| 引用本文： | 彭莉,张飞雄PENG Li,ZHANG Fei-xiong. SMC蛋白的结构和功能[J]. 遗传, 2001, 23(2): 173-276 |
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| 作者姓名： | 彭莉 张飞雄PENG Li ZHANG Fei-xiong |
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| 作者单位： | 首都师范大学生物系，北京 100037Department of Biology,Capital Normal University,Beijing 100037，China |
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| 摘 要： | 近年来新发现的一类蛋白――染色体结构维持蛋白(SMC蛋白，structural maintenance of chromosome proteins)与染色体结构细胞周期性的动态变化紧密相关，它们参与有丝分裂染色体的集缩和分离、性染色体的剂量补偿效应、姐妹染色单体的内聚作用(cohesion)、遗传重组和DNA修复等过程。本文从生化特性和生物学功能两方面叙述了对SMC蛋白的研究。Abstract：The newly discovered proteins, SMC (structural maintenance of chromosome) proteins, are associated with chromosome dynamics change in the cell cycle. They are involved in chromosome condensation, sister-chromatid cohesion, sex-chromosome dosage compensation, genetic recombination and DNA repair,etc. The current understanding of the biochemical properties and biological functions of SMC proteins is summarized in this paper.
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| 关 键 词： | 集缩蛋白 染色体结构维持蛋白 structural maintenance of chromosome proteins 内聚蛋白 Keywords condensins |
The Structure and Function of SMC Proteins |
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| PENG Li,ZHANG Fei-xiong. The Structure and Function of SMC Proteins[J]. Hereditas, 2001, 23(2): 173-276 |
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| Authors: | PENG Li ZHANG Fei-xiong |
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