|
|||||
|
|
C3'-cis-Substituted carboxycyclopropyl glycines as metabotropic glutamate 2/3 receptor agonists: synthesis and SAR studies |
|
| Authors: | González Rosario Collado Iván de Uralde Beatriz López Marcos Alicia Martín-Cabrejas Luisa M Pedregal Concepción Blanco-Urgoiti Jaime Pérez-Castells Javier Fernández M Alejandro Andis Sherri L Johnson Bryan G Wright Rebecca A Schoepp Darryle D Monn James A |
| Affiliation: | Lilly, Alcobendas, Madrid, Spain. gonzalez_rosario@lilly.com |
| Abstract: | The synthesis of a series of C3'-cis-substituted carboxycyclopropyl glycines bearing a wide variety of functional groups is described, and the structure-activity relationship for this series as agonists of group II metabotropic glutamate receptors is reported. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |