Prolactin and ergocryptine effects on mucus glycoproteins of the rat ileum |
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Authors: | Ophelia Gona |
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Institution: | (1) Department of Anatomy, CMDNJ-New Jersey Medical School, 07103 Newark, New Jersey, USA |
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Abstract: | Summary The present work reports observations from a first study on the effect of prolactin on mucous cells of the mammalian ileum. Sprague-Dawley rats were treated with prolactin or with the prolactin-inhibitor ergocryptine. Light microscopic histochemical study revealed that ergocryptine increased the number both of Alcian Blue-positive mucous cells and of the total number of mucous cells in the ileal crypts. Prolactin treatment apparently decreased the number of Alcian Blue pH 1.0-positive (sulphated glycoprotein-containing) mucous cells on the villi but was without effect on crypt cells. The implications of these observations are discussed. |
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