Structure of human serum cholinesterase |
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| Authors: | O Lockridge |
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| Institution: | Pharmacology Department, Medical Science I, M6322, University of Michigan, Ann. Arbor, MI 48109-0626, USA |
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| Abstract: | Human cholinesterase has recently been sequenced and cloned. It is a glycoprotein of 4 identical subunits, each subunit containing 9 carbohydrate chains and 3.5 disulfide bonds. Protein folding is likely to be very similar in human cholinesterase and Torpedo acetylcholinesterase. The cholinesterases have no significant sequence homology with the serine proteases and seem to belong to a separate serine esterase family. |
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