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冠心病三支病变置入Firebird2术后3年的随访研究
引用本文:张辉,李月蕊,刘洋,李彦平,荆晶,刘宏斌.冠心病三支病变置入Firebird2术后3年的随访研究[J].现代生物医学进展,2015,15(12):2262-2265.
作者姓名:张辉  李月蕊  刘洋  李彦平  荆晶  刘宏斌
作者单位:解放军总医院心血管内科
基金项目:全军医药卫生科研基金项目(11BJZ19)
摘    要:目的:通过对冠心病三支病变患者置入Firebird 2支架术后3年的随访,探讨Firebird 2支架的性能。方法:收集2009年1月~2012年12月在解放军总医院住院行冠脉造影确诊为冠心病且首次置入Firebird 2支架患者的临床资料,按术后随访时间不同分为术后3年组(70例)与术后1年组(69例),比较两组的临床资料及术后MACE的结果。结果:术后3年组再发心绞痛的比例显著高于术后1年组(33.8 vs 18.2)%,差异有统计学意义(P0.05)。而两组间性别、年龄、体重指数、SYNTAX积分、LVEF、优势血管(右)、既往史、诊断、NYHA心功能分级,MACE、再次血运重建、总死亡、非致死性心肌梗死及造影复查比例,支架总数及前降支、回旋支和右冠置入支架数比较均无统计学差异(P0.05)。结论:冠心病三支病变置入Firebird 2术后3年主要心血管不良事件的发生情况与术后1年相当,但还需大规模、多中心继续随访研究。

关 键 词:冠心病  Firebird  2  随访研究

3-year Follow-up after Firebird 2 Stent Implantation of Coronary Heart Disease patients with Three Lesions
Abstract:Objective:To explore the performance of Firebird 2 stents through the 3-year follow-up of coronary heart disease (CHD) patients with three lesions treated by Firebird 2 stents.Methods:From Jan. 2009 to Dec. 2009, the clinical data of CHD patients who underwent coronary angiography and were treated with Firebird 2 stents for the first time in our department were collected. According to the follow-up time, 70 patients were divided into 3-year group and 69 patients were divided into 1-year group. The major adverse cardiac or cerebrovascular events (MACCE) were compared between the two groups.Results:The recurrence of angina pectoris in 3-year group was significantly higher than that of 1-year group (33.8 vs 18.2) %. No significant difference was found in the gender, age, body mass index, SYNTAX score, LVEF, advantage blood vessels (right), past medical history, diagnosis, NYHA heart function classification, MACE, reascularization, total death, nonfatal myocardial infarction, proportion of repeated angiography, number of total stents, number of stents in LAD, LCX and RCA between the two groups (P>0.05).Conclusion:CHD patients presenting with 3-vessel lesions had the same occurrence rate of adverse cardiac events at 1st year and 3rd year post-operation. Further large and multicenter follow-up studies were still required.
Keywords:Coronary heart disease (CHD)  Firebird 2  Follow-up study
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