The bacterial degradation of flavonoids. Oxidative fission of the A-ring of dihydrogossypetin by a Pseudomonas sp |
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| Authors: | A. M. Jeffrey D. M. Jerina R. Self W. C. Evans |
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| Affiliation: | Department of Biochemistry and Soil Science, University College of North Wales, Bangor, Caerns., U.K., National Institute for Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Md. 20014, U.S.A., and Agricultural Research Council, Food Research Institute, Norwich NOR 70F, U.K. |
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| Abstract: | Cell-free extracts prepared from a Pseudomonas sp., grown on (+)-catechin, oxidized dihydrogossypetin (3',4',5,7,8-pentahydroxyflavanonol) by cleaving the A-ring to form oxaloacetic acid from C-5, C-6, C-7 and C-8 together with 5-(3,4-dihydroxyphenyl)-4-hydroxy-3-oxovalero-delta-lactone. The structure of this lactone was confirmed by synthesis of related phenylvalerolactones. |
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