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Mutation as an origin of genetic variability in Helicobacter pylori |
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| Authors: | Wang G Humayun M Z Taylor D E |
| Institution: | a Dept of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7 b University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Dept of Microbiology and Molecular Genetics, 185 South Orange Avenue, Newark, NJ 07103, USA |
| Abstract: | The availability of two complete Helicobacter pylori genome sequences and recent studies of its population genetics have provided a detailed picture of genetic diversity in this important human gastric pathogen. It is believed that, in addition to genetic recombination, de novo mutation could have a role in generating the high level of genetic variation in H. pylori. |
| Keywords: | Helicobacter pylori Genome sequences Genetic diversity Phenotypic variation Mutation and mutagenesis DNA repair |
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