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Discovery of novel hydroxy pyrazole based factor IXa inhibitor
Authors:Vijaykumar Dange  Sprengeler Paul A  Shaghafi Michael  Spencer Jeffrey R  Katz Brad A  Yu Christine  Rai Roopa  Young Wendy B  Schultz Brian  Janc James
Affiliation:Celera, 180 Kimball Way, South San Francisco, CA 94080, USA. dvijayku@hotmail.com
Abstract:Synthesis and biological data of a novel selective and efficacious factor IXa inhibitor are described along with its crystal structure in factor VIIa.
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