|
|||||
|
|
Minimotif Miner: a tool for investigating protein function |
|
| Authors: | Balla Sudha Thapar Vishal Verma Snigdha Luong Thaibinh Faghri Tanaz Huang Chun-Hsi Rajasekaran Sanguthevar del Campo Jacob J Shinn Jessica H Mohler William A Maciejewski Mark W Gryk Michael R Piccirillo Bryan Schiller Stanley R Schiller Martin R |
| Affiliation: | Department of Computer Science and Engineering, University of Connecticut, Storrs, Connecticut 06269, USA. |
| Abstract: | In addition to large domains, many short motifs mediate functional post-translational modification of proteins as well as protein-protein interactions and protein trafficking functions. We have constructed a motif database comprising 312 unique motifs and a web-based tool for identifying motifs in proteins. Functional motifs predicted by MnM can be ranked by several approaches, and we validated these scores by analyzing thousands of confirmed examples and by confirming prediction of previously unidentified 14-3-3 motifs in EFF-1. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |