Cytokinesis. |
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Authors: | L L Satterwhite T D Pollard |
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Institution: | Department of Cell Biology and Anatomy, Johns Hopkins Medical School, Baltimore, Maryland 21205. |
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Abstract: | The actomyosin contractile-ring mechanism remains the paradigm for cytokinesis after 20 years of experimental testing. Recent evidence suggests that Ca2+ triggers the contraction and that cell-cycle kinases regulate the timing of cytokinesis. New work is required to identify the signals from the mitotic spindle that specify the position of the furrow. |
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