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Orthobiologics in the treatment of hip disorders
作者姓名:Andre Vinicius Saueressig Kruel  Lucas Leite Ribeiro  Paulo David Gusmao  Stephany Cares Huber  Jose Fabio Santos Duarte Lana
作者单位:Department of Orthopedics;Department of Orthopedics;Department of Hematology;Department of Orthopedics
摘    要:Orthobiologics are biological materials that are intended for the regeneration or healing of bone,cartilage and soft tissues.In this review we discuss the use of orthobiologics for hip disorders providing an update.The orthobiologics included in this article are hyaluronic acid,platelet rich plasma,bone marrow,adipose tissue and expanded mesenchymal stem cells.We explain the concepts and definitions of each orthobiological product,and the literature regarding its use in the hip joint.The paucity of guidelines for the production and characterization of the biological products leads to uneven results across the literature.Each biologic therapy has indications and benefits;however,noteworthy are the characterization of the orthobiologics,the application method and outcome analysis for further improvement of each technique.

关 键 词:Orthobiologics  Hip  disorders  Platelet-rich  plasma  Mesenchymal  stem  cells  Bone  marrow  Adipose  tissue
收稿时间:October 14, 2020

Orthobiologics in the treatment of hip disorders
Andre Vinicius Saueressig Kruel,Lucas Leite Ribeiro,Paulo David Gusmao,Stephany Cares Huber,Jose Fabio Santos Duarte Lana.Orthobiologics in the treatment of hip disorders[J].World journal of stem cells,2021,13(4):304-316.
Authors:Andr&#  Vin&#  cius Saueressig Kruel  Lucas Leite Ribeiro  Paulo David Gusm&#  o  Stephany Cares Huber  Jos&#  F&#  bio Santos Duarte Lana
Abstract:Orthobiologics are biological materials that are intended for the regeneration or healing of bone, cartilage and soft tissues. In this review we discuss the use of orthobiologics for hip disorders providing an update. The orthobiologics included in this article are hyaluronic acid, platelet rich plasma, bone marrow, adipose tissue and expanded mesenchymal stem cells. We explain the concepts and definitions of each orthobiological product, and the literature regarding its use in the hip joint. The paucity of guidelines for the production and characterization of the biological products leads to uneven results across the literature. Each biologic therapy has indications and benefits; however, noteworthy are the characterization of the orthobiologics, the application method and outcome analysis for further improvement of each technique.
Keywords:Orthobiologics  Hip disorders  Platelet-rich plasma  Mesenchymal stem cells  Bone marrow  Adipose tissue
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