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| 人工肝支持系统(ALSS)治疗重型乙肝患者血清细胞因子表达 | |
| 引用本文： | 安俊丽,吴玮,蔡杰超,张文忠,庄园. 人工肝支持系统(ALSS)治疗重型乙肝患者血清细胞因子表达[J]. 现代生物医学进展, 2012, 12(33): 6463-6465 |
| 作者姓名： | 安俊丽 吴玮 蔡杰超 张文忠 庄园 |
| 作者单位： | 1. 青岛大学医学院附属青岛市传染病医院肝病科 山东青岛266071 2. 漯河医专二附院 河南漯河462000 3. 青岛大学医学院附属医院心内科 山东青岛266071 4. 青岛市传染病医院肝病科 山东青岛266071 |
| 摘 要： | 目的:探讨人工肝支持系统治疗重型乙肝的临床疗效.方法:将80例重型乙肝分为对照组和实验组,对照组40例,仅做一般内科治疗,实验组40例,在内科治疗基础上行人工肝支持系统治疗,每周2-3次,观察8周.采用ELISA法检测重型乙肝患者血清IL-2、TNF-α及TGF-β1水平在各组治疗后表达,数据进行统计学处理.结果:ALSS治疗后较对照组TNF-α及TGF-β1水平明显下降,而IL-2水平则呈上升趋势.结论:ALSS治疗能降低重型乙肝患者TNF-α及TGF-β1含量,并升高IL-2水平,从而抑制炎性介质的产生,减轻免疫反应对肝细胞的损伤,提高重型乙肝的存活率. |
| 关 键 词： | 人工肝 乙型肝炎 细胞因子 |
The Effect of Artificial Liver Supporting System (ALSS) on the Treatment of Severe Patients of Hepatitis B: A View from the Serum Cytokine |
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| AN Jun-li,WU Wei,△ , CAI Jie-chao,ZHANG Wen-zhong,ZHUANG Yuan. The Effect of Artificial Liver Supporting System (ALSS) on the Treatment of Severe Patients of Hepatitis B: A View from the Serum Cytokine[J]. Progress in Modern Biomedicine, 2012, 12(33): 6463-6465 | |
| Authors: | AN Jun-li WU Wei △ CAI Jie-chao ZHANG Wen-zhong ZHUANG Yuan |
| Affiliation: | 1 Department of Liver, Infectious Disease Hospital of Qingdao University, Medicine College ,Qingdao, Shandong, 266071, China; 2 The Second Affiliated Hospital of Luohe Medicine College, Luohe, Henan, 462000,China; 3 Department of Heart,the Affiliated Hospital of Qingdao University Medical College, Qingdao, Shandong, 266071, China; 4 Department of Liver, Municipal Hospital for Infectious Disease of Qingdao , Qingdao, Shandong, 266071,China) |
| Abstract: | |
| Keywords: | ALSS Hepatitis B Cytokine |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |