盐酸戊乙奎醚与丙泊酚联合用于无痛人工流产术的临床研究

目的:评价盐酸戊乙奎醚联合丙泊酚减轻人工流产术后疼痛的效果.方法:ASAⅠ-H级人工流产术患者100例,随机分为观察组和对照组.处理组先缓慢静脉注射盐酸戊乙奎醚注射剂1mg,30min后静脉注射丙泊酚2.5mg/kg;;对照组单独静脉注射丙泊酚2.5mg/kg.两组丙泊酚静注速率均为5mg/s.结果:处理组苏醒即刻苏醒后15min和30min宫缩痛的VAS评分分别为(3.13±0.15)、(2.02±0.11)和(0.87±0.09)分,明显低于对照组的(4.47± 0.35)、(3.54± 0.14)及(2.01±0.12)(P＜0.01).结论:盐酸戊乙奎醚联合丙泊酚镇痛能减轻人工流产术后的疼痛.

Effect of Penehyclidine Hydrochloride with Propofol Analgesia on the Postoperative Pain in Painless Artificial Abortion

Objective： To evaluate the effect of Penehyclidine Hydrochloride with propofol analgesia on the postoperative pain in painless artificial abortion.Methods： One hundred ASA I-II patients undergoing artificial abortion were randomly assigned to two groups（n=50 each）： control group（con） were was administrated propofol 2.5mg/kg alone.Treatment group was administrated intravenously Penehyclidine Hydrochloride 1mg followed by propofol 2.5mg/kg 30minutes later.The speed of intravenously injection of propofol was 5mg/s in two groups.Results： The VAS scores at immediate time of awaked from anesthesia,15min and 30min after that were（3.13± 0.15）、（2.02±0.11）and（0.87±0.09）,respectively,in treatment group,which were significantly shorter than（4.47±0.35）、（2.02± 0.11）and（2.01±0.12）in control grouo（P0.01）.Conclusion： Penehyclidine Hydrochloride combined with propofol anesthesia can effectively relieve the postoperative pain of artificial abortion.