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我院2008-2011年抗菌药物使用量与铜绿假单胞菌耐药相关性的研究
引用本文:曾晓媛,杨红忠,彭毅强,邱湘玲,欧艳.我院2008-2011年抗菌药物使用量与铜绿假单胞菌耐药相关性的研究[J].现代生物医学进展,2012,12(34):6772-6774,6791.
作者姓名:曾晓媛  杨红忠  彭毅强  邱湘玲  欧艳
作者单位:湖南省长沙市中心医院呼吸内科 湖南长沙410011
摘    要:目的:探讨2008-2011年我院抗菌药物使用与铜绿假单胞菌(PA)耐药水平变化之间的关系.方法:计算10种抗菌药物平均每日每百张床住所消耗的限定日剂量(DDD)及同期PA的耐药率,并对抗菌药物用量与耐药率进行相关性分析.结果:发现头孢哌酮/舒巴坦及左氧氟沙星DDD分别与铜绿假单胞菌对头孢噻肟、头孢吡肟、左氧氟沙星、亚胺培南、头孢噻肟、头孢哌酮/舒巴坦、头孢吡肟耐药率的相关性有统计学意义,其它组数据无统计学意义.结论:呼吸病区左氧氟沙星及头孢哌酮/舒巴坦DDD的使用量与PA耐药率相关.

关 键 词:铜绿假单胞菌  耐药率  抗菌药物使用频度

Analysis of Correlation between Consumption of Anti- bacterial Agents and Resistant Rate of Pseudomonas Aeruginosa in our Hospital
ZENG Xiao-yuan,YANG Hong-zhong,PENG Yi-qiang,QIU Xiang-ling,OU Yan.Analysis of Correlation between Consumption of Anti- bacterial Agents and Resistant Rate of Pseudomonas Aeruginosa in our Hospital[J].Progress in Modern Biomedicine,2012,12(34):6772-6774,6791.
Authors:ZENG Xiao-yuan  YANG Hong-zhong  PENG Yi-qiang  QIU Xiang-ling  OU Yan
Institution:(Department of Respirotary medicine Central Hospital of Changsha,Hunan Changsha,410011,China)
Abstract:Objective: To investigate the relationship between administration of anti-bacterial agents and resistant rate of Pseudomonas aeruginosa(PA) in our hospital.Methods: The defined daily dose(DDD) of ten kinds of anti-bacterial was calculated;and the resistant rate of PA at that period was collected;and their correlation was analyzed.Results: There was a significant positive correlation between the consumption of cefoperazone,sulbactam,levofloxacin and the resistant rate of PA of cefotaxime,efepime,levofloxacin,imipenem,cefotaxime,cefoperazone sulbactam and efepime.Conclusion: The consumption of anti-bacterial agents was related with the resistant rate of PA in our hospital.
Keywords:Pseudomonas aeruginosa  Drug resistance  Consumption of anti-bacterial agents
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