Monoamine oxidase and semicarbazide sensitive amine oxidase activities in toad liver mitochondria |
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Authors: | O Senatori A Nicotra |
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Institution: | Dipartimento di Biologia Animale e dell'Uomo, Università di Roma, Italy. |
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Abstract: | 1. The deamination of 5-HT and PEA has been assayed by a radiochemical method in mitochondria isolated from toad liver. 2. Time courses of 5-HT and PEA deamination indicate that when PEA is used as the substrate, higher specific activities are obtained. 3. 5-HT is deaminated by MAO A and partially by a SSAO-like enzyme. 4. PEA is deaminated exclusively by SSAO and, MAO B activity, at least under the adopted experimental conditions, is not detectable. |
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