超声空化效应和超声微泡在生物医学中的应用

近年来，随着超声技术在医疗领域的广泛应用及超声造影剂研制的进展，空化效应和超声造影剂协同运用作为一种高效、安全、操作简单，且具有一定靶向性的无创治疗手段，在基因治疗、药物输送、溶栓和治栓，以及炎症与肿瘤的靶向诊断与治疗方面显示了巨大的运用潜力。简要综述了超声空化效应和超声微泡的治疗机制及应用。

Applications of Ultrasonic Cavitation and Ultrasound Microbubbles in Biomedicme and Therapy

With the developments and therapeutic applications of ultrasound techniques and advances in ultrasound contrast agents in recent years, the synergistic effects of ultrasonic cavitation and ultrasound contrast agents, as an efficient, safe, simple and targeted therapy with no pain, has shown great potential in biomedicine such as gene therapy, drug delivery, thrombus lysis and diagnosis and therapy for vascular diseases and tumors. The mechanism and applications in therapy of ultrasonic cavitation and ultrasound contrast agents were reviewed in this paper.