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Mutant TDP-43 Expression Triggers TDP-43 Pathology and Cell Autonomous Effects on Primary Astrocytes: Implications for Non-cell Autonomous Pathology in ALS |
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| Authors: | Barton Samantha K. Lau Chew L. Chiam Mathew D. F. Tomas Doris Muyderman Hakan Beart Philip M. Turner Bradley J. |
| Affiliation: | 1.Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, 3052, Australia ;2.Centre for Neuroscience and Discipline of Medical Biochemistry, Flinders Medical Science and Technology, College of Medicine & Public Health, Flinders University, Adelaide, SA, Australia ; |
| Abstract: | Neurochemical Research - Motor neuron degeneration in amyotrophic lateral sclerosis (ALS) caused by mutations in superoxide dismutase 1 (SOD1) is partly non-cell autonomous, involving cellular... |
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