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P-glycoprotein inhibitory activity of two phenolic compounds, (-)-syringaresinol and tricin from Sasa borealis
Authors:Jeong Yeon Hee  Chung Soo Yeon  Han Ah-Reum  Sung Min Kyung  Jang Dae Sik  Lee Jun  Kwon Youngjoo  Lee Hwa Jeong  Seo Eun-Kyoung
Institution:College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea.
Abstract:(-)-Syringaresinol and tricin, isolated from the AcOEt-soluble extract of the whole plants of Sasa borealis (Gramineae), showed inhibitory effects on the P-glycoprotein in adriamycin-resistant human breast cancer cells, MCF-7/ADR.
Keywords:P‐Glycoprotein  Sasa borealis  (–)‐Syringaresinol  Tricin  Inhibitors  Breast cancer
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