A new metabolite with a new substitution pattern from the seeds of the Chinese Yew, Taxus mairei |
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| Authors: | Huo Chang-Hong Wang Yu-Fang Zhang Xi-Ping Li Cun-Fang Shi Qing-Wen Kiyota Hiromasa |
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| Institution: | Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, 050017, Shijiazhuang, Hebei Province, PR China. |
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| Abstract: | A new taxoid metabolite with a new substitution pattern was isolated from the methanol extract of the seeds of Taxus mairei, and its structure was established as 5alpha,15-dihydroxy-7beta,9alpha-diacetoxy-11(15-->1)abeo-taxa-4(20),11-dien-13-one (1) on the basis of spectral analysis including (1)H- and (13)C-NMR, HMQC, HMBC, NOESY, and confirmed by HR-FAB mass spectrometry. |
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| Keywords: | Taxus mairei Diterpenoids Metabolites Taxoids |
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