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Effect of amyloid beta on ATP-binding cassette transporter expression and activity in porcine brain microvascular endothelial cells |
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| Authors: | Maryam H. Shubbar Jeffrey I. Penny |
| Affiliation: | Division of Pharmacy & Optometry, University of Manchester, Manchester M13 9PT, UK |
| Abstract: | |
| Keywords: | ABCB1 ABCG2 ABCC5 Nuclear receptors Amyloid-β Alzheimer's disease Porcine brain endothelial cells ABC ATP-binding cassette (1–42) BBB blood–brain barrier CAR constitutive androstane receptor CAPS 3-(Cyclohexylamino)-1-propanesulfonic acid CMFDA chloromethylfluorescein diacetate DMEM Dulbecco's Modified Eagle's medium GS–MF glutathione methyl fluorescein hAPP human amyloid precursor protein LRP low density lipoprotein PBEC porcine brain endothelial cell PXR Pregnane X receptor RAGE the receptor for advanced glycation end products |
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