A novel pathway of peptide biosynthesis found in methanogenic Archaea |
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Authors: | Evanmarie Hartmann Helmut König |
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Institution: | 1. Angewandte Mikrobiologie, Universit?t Ulm, D-89069, Ulm, Germany
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Abstract: | The peptide subunits of the pseudomurein, the cell-wall peptidoglycan of some methanogens, are usually composed of glutamic
acid, alanine and lysine. In order to get a more detailed picture of the biosynthetic pathway of the peptide subunit, we performed
in vitro assays. Starting from glutamic acid a pentapeptide was obtained in seven steps:
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