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Influence of RGD-containing oligopeptide-coated surface on bone formation in vitro and in vivo |
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| Authors: | Tae-Il Kim Gene Lee Jun-Hyeog Jang Chong-Pyoung Chung Young Ku |
| Affiliation: | (1) Department of Periodontology, Intellectual Biointerface Engineering Center, Seoul National University, Seoul, 110-768, South Korea;(2) Department of Craniomaxillofacial Reconstructive Science, Dental Research Institute, College of Dentistry, Seoul National University, Seoul, 110-768, South Korea;(3) Department of Biochemistry and BK21 CAME, College of Medicine, Inha University, Incheon, 400-712, South Korea |
| Abstract: | New bone formation on an RGD-containing oligopeptide-coated surface in vitro and in vivo was investigated. The surface showed two-fold higher osteoblastic cell adhesion and differentiation in vitro, and revealed statistically significant in vivo bone formation compared with the control (P < 0.05). |
| Keywords: | Bone Cell adhesion Extracellular matrix Fibronectin Osteoblast |
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