Taxon ordering in phylogenetic trees: a workbench test |
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Authors: | Francesco Cerutti Luigi Bertolotti Tony L Goldberg Mario Giacobini |
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Affiliation: | (1) Department of Animal Production, Epidemiology and Ecology, Faculty of Veterinary Medicine, University of Torino, via Leonardo da Vinci 44, 10095 Grugliasco (TO), Italy;(2) Molecular Biotechnology Center, University of Torino, via Nizza 52, 10126 Torino, Italy;(3) Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 1656 Linden Drive, Madison, Wisconsin 53706, USA |
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Abstract: | Background Phylogenetic trees are an important tool for representing evolutionary relationships among organisms. In a phylogram or chronogram, the ordering of taxa is not considered meaningful, since complete topological information is given by the branching order and length of the branches, which are represented in the root-to-node direction. We apply a novel method based on a (λ + μ)-Evolutionary Algorithm to give meaning to the order of taxa in a phylogeny. This method applies random swaps between two taxa connected to the same node, without changing the topology of the tree. The evaluation of a new tree is based on different distance matrices, representing non-phylogenetic information such as other types of genetic distance, geographic distance, or combinations of these. To test our method we use published trees of Vesicular stomatitis virus, West Nile virus and Rice yellow mottle virus. |
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