Involvement of endorphins in emotional hyperthermia of rats |
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Authors: | Julia Bläsig Volker Höllt Ursual Bäuerle Albert Herz |
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Affiliation: | Department of Neuropharmacology, Max-Planck-Institut für Psychiatrie, Kraepelinstrasse 2, 8000 München 40, Federal Republic of Germany |
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Abstract: | When rats were confronted with the novel experience of a new environment and stressful handling procedure their body temperature increased within minutes. At the same time β-endorphin-like immunoreactivity in the plasma increased dramatically. The stress-induced hyperthermia could be antagonized or reversed by the active, not however, by the inactive enantiomer of naloxone. The data provide evidence for a physiological role of endorphins. |
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