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Asymmetric and non-uniform evolution of recently duplicated human genes |
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| Authors: | Alexander Y Panchin Mikhail S Gelfand Vasily E Ramensky Irena I Artamonova |
| Institution: | (1) M.V. Lomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics, Vorobyevy Gory 1-73, Moscow, 119992, Russia;(2) A.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Science, Bolshoi Karetny 19, Moscow, 127994, Russia;(3) V.A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova 32, Moscow, 119991, Russia;(4) N.I. Vavilov Institute of General Genetics, Russian Academy of Science, Gubkina 3, Moscow, 119991, Russia |
| Abstract: | BackgroundGene duplications are a source of new genes and protein functions. The innovative role of duplication events makes families of paralogous genes an interesting target for studies in evolutionary biology. Here we study global trends in the evolution of human genes that resulted from recent duplications. |
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