Partial reaction of peptide initiation inhibited by the reticulocyte hemin-controlled repressor |
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Authors: | Pairoh Pinphanichakarn Gisela Kramer Boyd Hardesty |
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Affiliation: | Clayton Foundation Biochemical Institute Department of Chemistry, The University of Texas Austin, Texas 78712 USA |
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Abstract: | The hemin-controlled repressor from rabbit reticulocytes inhibits binding of Met-tRNAf to reticulocyte 40S ribosomal subunits in a partial reaction containing these components, two initiation factor fractions and GTP. The inhibitor does not interfere with the formation of the Met-tRNAf· initiation factor IF-E2·GTP complex. |
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