Chromatin subunit small angle neutron scattering: A DNA rich coil surrounds a protein-DNA core |
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| Authors: | P. Baudy S. Bram D. Vastel J. Lepault A. Kitzis |
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| Affiliation: | 1. Institut du Radium Bat. 112, Universitéde Paris Sud 91405, Orsay, France;2. Institut Pasteur 75024 Paris, France |
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| Abstract: | The small angle neutron scattering radii of gyration of 185 base pair subunits have been determined in H2O and D2O These values suggest that the outer diameter is 120 to 150Å. The results are not consistent with models in which all of the DNA is in an external shell. The neutron scattering profiles are in good agreement with a model based upon freeze etching electron microscopy (4) having two concentric coils of DNA with 80Åand 150Åexternal diameters. |
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