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Intraspecies antagonism of Sh. flexneri in an HEp-2 cell line model]
Authors:V M Bondarenko  N M Iuditskaia  V G Petrovskaia
Abstract:The authors describe an effect of suppression of invasion of the guinea pig eye conjunctiva and the HEp-2 epithelial cells by virulent Sh. flexneri bacilli, with a simultaneous administration of the same dose of avirulent shigella mutants, genetically connected with them. The data of morphological study and experiments with 3H-glucose labeled shigellae carried out on the cell species model indicated that the bacterial competition for the specific sites for absorption on the epithelial cells underlay the observed phenomenon.
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