Measurements of total body calcium by prompt-gamma neutron activation abalysis using a252Cf source |
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Authors: | Ryde S. J. S. Morgan W. D. Compston J. Evans C. J. Sivyer A. Dutton J. |
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Affiliation: | 1.Department of Medical Physics and Clinical Engineering, Singleton Hospital, SA2 8QA, Swansea, Wales, UK ;2.Department of Pathology, University of Wales College of Medicine, Heath Park, CF4 4XN, Cardiff, Wales, UK ;3.Department of Physics, University College of Swansea, SA2 8PP, Swansea, Wales, UK ; |
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Abstract: | A clinical neutron activation instrument has been developed for in vivo elemental analysis. Utilizing the prompt-capture gamma ray technique, simultaneous total body (TB) measurements of primarily Ca, but also Cl, N, C, and H are routinely performed. This paper describes a technique for the measurement of TBCa (g) that relies on the use of TBCl as an internal standard. The method has been tested with four anthropomorphic phantoms covering a range of body habitus. The mean discrepancy between the measured and known Ca contents was 3.6%. The technique has been applied to two patient groups, and encouraging results were obtained. |
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Keywords: | KeywordHeading" >Index Entries In vivo neutron activation analysis Ca measurement neutron activation analysis body composition analysis Ca, in vivo measurement of 252Cf prompt gamma ray neutron activation total body calcium |
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