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Measurements of total body calcium by prompt-gamma neutron activation abalysis using a252Cf source
Authors:Ryde  S. J. S.  Morgan  W. D.  Compston  J.  Evans  C. J.  Sivyer  A.  Dutton  J.
Affiliation:1.Department of Medical Physics and Clinical Engineering, Singleton Hospital, SA2 8QA, Swansea, Wales, UK
;2.Department of Pathology, University of Wales College of Medicine, Heath Park, CF4 4XN, Cardiff, Wales, UK
;3.Department of Physics, University College of Swansea, SA2 8PP, Swansea, Wales, UK
;
Abstract:A clinical neutron activation instrument has been developed for in vivo elemental analysis. Utilizing the prompt-capture gamma ray technique, simultaneous total body (TB) measurements of primarily Ca, but also Cl, N, C, and H are routinely performed. This paper describes a technique for the measurement of TBCa (g) that relies on the use of TBCl as an internal standard. The method has been tested with four anthropomorphic phantoms covering a range of body habitus. The mean discrepancy between the measured and known Ca contents was 3.6%. The technique has been applied to two patient groups, and encouraging results were obtained.
Keywords:  KeywordHeading"  >Index Entries In vivo neutron activation analysis  Ca measurement  neutron activation analysis  body composition analysis  Ca, in vivo measurement of   252Cf  prompt gamma ray neutron activation  total body calcium
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