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Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives |
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| Authors: | Takayama Wataru Shirasaki Yoshihisa Sakai Yusuke Nakajima Emi Fujita Shuhei Sakamoto-Mizutani Kanako Inoue Jun |
| Institution: | Research Laboratories, Senju Pharmaceutical Co., Ltd., 1-5-4 Murotani, Nishi-Ku, Kobe, Hyogo 651-2241, Japan. yingshe-cui@senju.co.jp |
| Abstract: | A novel series of benzothiazolylidenehydroxamic acid derivatives has been designed and synthesized as PDF inhibitors. Some of this novel class of PDF inhibitors exhibited micromolar order enzyme inhibitory activity and antibacterial activity. |
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