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MotifAdjuster: a tool for computational reassessment of transcription factor binding site annotations |
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| Authors: | Jens Keilwagen Jan Baumbach Thomas A Kohl Ivo Grosse |
| Affiliation: | 1. Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben (IPK), Corrensstra?e 3, 06466, Gatersleben, Germany 2. International Computer Science Institute, 1947 Center Street, Berkeley, California, 94704, USA 3. International NRW Graduate School in Bioinformatics and Genome Research, Center for Biotechnology (CeBiTec), Bielefeld University, Universit?tsstra?e 27,, 33615, Bielefeld, Germany 4. International NRW Graduate School in Bioinformatics and Genome Research, Center for Biotechnology (CeBiTec), Bielefeld University, Universit?tsstra?e 27,, 33615, Bielefeld, Germany 5. Institute of Computer Science, Martin Luther University Halle-Wittenberg, Von-Seckendorff-Platz 1, 06120, Halle, Germany |
| Abstract: | Valuable binding-site annotation data are stored in databases. However, several types of errors can, and do, occur in the process of manually incorporating annotation data from the scientific literature into these databases. Here, we introduce MotifAdjuster , a tool that helps to detect these errors, and we demonstrate its efficacy on public data sets. |
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