Thermodynamics of interaction of phthalocyanine-oligonucleotide conjugates with single- and double-stranded DNA |
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| Authors: | Chernonosov A A Kuznetsov N A Koval V V Pyshnyi D V Derkacheva N M Lukyanets E A Fedorova O S |
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| Affiliation: | Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia. |
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| Abstract: | Thermodynamics of interaction of phthalocyanine-oligonucleotide conjugates with single- and double-stranded DNA resulting in formation of duplexes and triplexes was measured by UV melting method. It was shown that a phthalocyanine moiety of conjugates stabilized the formation of duplexes and triplexes. |
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