STUDIES ON MILK SECRETION : THE INFLUENCE OF INANITION

In this paper data are presented on cows receiving no food but having access to all of the water which they wished. The yield and composition of the milk were determined at various times during the periods of starvation. The composition of the milk showed changes which were progressive in the sense that they followed a definite course. They were characterized by a marked lowering in the amount of milk produced, by an increase in the total solids (chiefly an increase in the percentage of fat and ash, with a slight increase in proteins), and by a pronounced decrease in the lactose. The decrease in lactose corresponded with a decrease in the dextrose content of the blood, thereby supporting the conclusion that the lactose of milk has as its precursor dextrose of the blood. All the changes in milk composition during starvation can be directly related to the simultaneous changes in the blood. The following companion paper on insulin and phloridzin as they affect milk secretion further develops these hypotheses.