|
|||||
|
|
Isolation and identification of oligomeric procyanidins from Crataegus leaves and flowers |
|
| Authors: | Svedström Ulla Vuorela Heikki Kostiainen Risto Tuominen Jari Kokkonen Juha Rauha Jussi-Pekka Laakso Into Hiltunen Raimo |
| Affiliation: | a Department of Pharmacy, Division of Pharmacognosy, University of Helsinki, PO Box 56, FIN-00014, Helsinki, Finland b Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Helsinki, PO Box 56, FIN-00014, Helsinki, Finland c Viikki Drug Discovery Technology Center, Department of Pharmacy, University of Helsinki PO Box 56, FIN-00014, Helsinki, Finland d Lahden Tutkimuslaboratorio, Niemenkatu 73 C, 15140, Lahti, Finland e VTT Chemical Technology, PO Box 1401, FIN-02044 VTT, Finland |
| Abstract: | Oligomeric procyanidins were isolated from the leaves and flowers of hawthorn (Crataegus laevigata). A trimer, epicatechin-(4β→8)-epicatechin-(4β→6)-epicatechin, and a pentamer consisting of (−)-epicatechin units linked through C-4β/C-8 bonds have been isolated from hawthorn for the first time, in addition to known procyanidins including dimers B-2, B-4 and B-5, trimers C-1 and epicatechin-(4β→6)-epicatechin-(4β→8)-epicatechin, and tetramer D-1. A fraction containing a hexamer was also found. |
| Keywords: | Crataegus laevigata Rosaceae Hawthorn Oligomeric procyanidins Condensed tannins ESI–MS |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |