Localization of the structural genes for hexokinase-1 and inorganic pyrophosphatase on region (pter-->q24) of human chromosome 10

Concordant expression of human hexokinase-1 and inorganic pyrophosphatase was established in somatic cell hybrids between thymidine kinase-deficient Chinese hamster cells and human fibroblasts carrying a translocation of the distal third of the long arm of chromosome 10 to chromosome 17. Neither human hexokinase-1 nor human inorganic pyrophosphatase expression segregated concordantly with human cytoplasmic glutamic-oxaloacetic transaminase expression.