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Procarcinogenic effects of cyclosporine A are mediated through the activation of TAK1/TAB1 signaling pathway |
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| Authors: | Xu Jianmin Walsh Stephanie B Verney Zoe M Kopelovich Levy Elmets Craig A Athar Mohammad |
| Institution: | aDepartment of Dermatology, University of Alabama at Birmingham, AL 35294, USA;bSkin Diseases Research Center, University of Alabama at Birmingham, AL 35294, USA;cDivision of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA |
| Abstract: | |
| Keywords: | Abbreviations: CsA cyclosporine A TAK1 tumor growth factor β-activated kinase1 TAB1 TAK binding protein 1 NFκB nuclear factor κB NMSC non-melanoma skin cancer SCC squamous cell carcinoma BCC basal cell carcinoma UVB ultraviolet B OTRs organ transplant recipients MPP mitochondrial permeability pore VEGF vascular endothelial growth factor IκB inhibitory κB IKKβ IκB kinase β IRAK interleukin-1 receptor associated kinase AMPK AMP-activated protein kinase |
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