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An Mdm2 antagonist, Nutlin-3a, induces p53-dependent and proteasome-mediated poly(ADP-ribose) polymerase1 degradation in mouse fibroblasts |
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| Authors: | Matsushima Shingo Okita Naoyuki Oku Misako Nagai Wataru Kobayashi Masaki Higami Yoshikazu |
| Affiliation: | Department of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Yamazaki 2641, Noda, Chiba 278-0022, Japan |
| Abstract: | |
| Keywords: | Nutlin-3a Poly(ADP-ribose) polymerase1 p53 Mdm2 Proteasome |
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