Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein,phosphodontin |
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Authors: | Karlheinz Mann Albert J Poustka Matthias Mann |
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Affiliation: | 1.Max-Planck-Institut für Biochemie,Abteilung Proteomics und Signaltransduktion,Martinsried,Germany;2.Max-Planck-Institut für Molekulare Genetik,Evolution and Development Group,Berlin,Germany |
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Abstract: | Background Sea urchin is a major model organism for developmental biology and biomineralization research. However, identification of proteins involved in larval skeleton formation and mineralization processes in the embryo and adult, and the molecular characterization of such proteins, has just gained momentum with the sequencing of the Strongylocentrotus purpuratus genome and the introduction of high-throughput proteomics into the field. |
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