Metabolites from the endophytic fungus Xylaria sp. PSU-D14 |
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| Authors: | Pongcharoen Wipapan Rukachaisirikul Vatcharin Phongpaichit Souwalak Kühn Till Pelzing Matthias Sakayaroj Jariya Taylor Walter C |
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| Institution: | Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla 90112, Thailand. |
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| Abstract: | Glucoside derivatives, xylarosides A (1) and B (2), were isolated from the broth extract of the endophytic fungus Xylaria sp. PSU-D14 along with two known compounds, sordaricin (3) and 2,3-dihydro-5-hydroxy-2-methyl-4H-1-benzopyran-4-one (4). The structures were assigned by spectroscopic methods. Sordaricin (3), one of the known metabolites, exhibited moderate antifungal activity against Candida albicans ATCC90028 with a MIC value of 32 microg/ml. |
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| Keywords: | Xylaria sp Glucosides Sordaricin Benzopyranones |
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