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SLFN11 Blocks Stressed Replication Forks Independently of ATR |
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| Authors: | Junko Murai Sai-Wen Tang Elisabetta Leo Simone A. Baechler Christophe E. Redon Hongliang Zhang Muthana Al Abo Vinodh N. Rajapakse Eijiro Nakamura Lisa M. Miller Jenkins Mirit I. Aladjem Yves Pommier |
| Affiliation: | 1. Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA;2. DSK project, Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8397, Japan;3. Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA |
| Abstract: |  |
| Keywords: | SLFN11 hydroxyurea camptothecin ATR cell cycle checkpoints PARP inhibitors prexasertib (LY2606368) replication origin CHK1 ATAC-seq |
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